This updated review concludes that zoledronate (Zometa) appears to be superior to both etidronate (Didronel) and placebo. However, it was not superior to pamidronate (Aredia) or clodronate (Bonefos) for improving overall survival or any other outcome, such as vertebral and nonvertebral fractures.
We were SO HAPPY when they switched Dominic from Aredia to Zometa. Infusions went from a couple of hours down to about 15 minutes. Plus, the Aredia left him laying in bed the next day for about the 1st 6 months.